| SYNTHESIS OF TRIFLUOROMETHYL-IMINES BY SOLID ACID/SUPERACID CATALYZED MICROWAVE ASSISTED APPROACH. | |
| | |
MedLine Citation:
|
PMID: 21949445 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
A new solid acid/superacid catalyzed microwave assisted synthesis of trifluoromethyl-imines is described. Various α,α,α-trifluoromethylketones react readily with primary amines to produce the corresponding imines. Two different strategies have been employed; one is the application of microwave irradiation coupled with solvent-free solid acid catalysis. The other method, for highly deactivated substrates includes the use of a pressure vessel at 175 °C temperature, with solid superacid catalysis. Using the solid acid K-10 montmorillonite or the superacidic perfluorinated resinsulfonic acid Nafion-H, a wide variety of trifluoromethylated imines have been synthesized using the above methods. The products have been isolated in good to excellent yields and high selectivities. This new environmentally friendly synthetic methodology provides significantly higher yields than traditional methods during relatively short reaction times for the preparation of the target compounds. |
| | |
Authors:
|
Mohammed Abid; Markku Savolainen; Shainaz Landge; Jinbo Hu; G K Surya Prakash; George A Olah; Béla Török |
Related Documents
:
|
6671975 - Studies on subunit assembly of broad bean legumin in a reconstitution system. 17144295 - Structural analysis of oligomeric molecules formed from the reaction products of oleic ... 20478375 - Effect of phosphoric acid pretreatment on enzymatic hydrolysis of microcrystalline cell... 15058995 - Characteristics of immobilized lipase on hydrophobic superparamagnetic microspheres to ... 16321455 - Production and characterization of recombinant vitellogenesis-inhibiting hormone from t... 10820085 - Formation of the mutagen ifp in model systems and detection in restaurant meats. |
Publication Detail:
|
Type: JOURNAL ARTICLE |
Journal Detail:
|
Title: Journal of fluorine chemistry Volume: 128 ISSN: 0022-1139 ISO Abbreviation: - Publication Date: 2007 Jun |
Date Detail:
|
Created Date: 2011-9-27 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0373322 Medline TA: J Fluor Chem Country: - |
Other Details:
|
Languages: ENG Pagination: 587-594 Citation Subset: - |
Affiliation:
|
Department of Chemistry, University of Massachusetts Boston, 100 Morrissey Blvd. Boston, MA 02132-3393, USA. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
| Grant Support | |
ID/Acronym/Agency:
|
R15 AG025777-02//NIA NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Academic Giftedness and Alcohol Use in Early Adolescence.
Next Document: Importing the Poor: Welfare Magnetism and Cross-Border Welfare Migration.