Document Detail

Synthesis of sulfated pectins and their anticoagulant activity.
MedLine Citation:
PMID:  20636268     Owner:  NLM     Status:  MEDLINE    
The following pectins were sulfated: bergenan BC (the pectin of Bergenia crassifolia L), lemnan LM (the pectin of Lemna minor L), and galacturonan as a backbone of pectins. Pyridine monomethyl sulfate, pyridine sulfotrioxide, and chlorosulfonic acid were used as reagents for sulfation. Chlorosulfonic acid proved to be the optimal reagent for sulfation of galacturonan and other pectins. Galacturonan and pectin derivatives with different degrees of sulfation were synthesized and their anticoagulant activities were shown to depend on the quantity of sulfate groups in the pectin macromolecules.
F V Vityazev; V V Golovchenko; O A Patova; N N Drozd; V A Makarov; A S Shashkov; Yu S Ovodov
Related Documents :
1905488 - Sulfation by human lung fibroblasts: so4(2-) and sulfur-containing amino acids as sourc...
10836748 - Isolation and characterization of proteoglycan derived from human placenta and its biol...
15465128 - Microbial dechlorination of dioxins in estuarine enrichment cultures: effects of respir...
23910338 - Investigation of emulsified, acid and acid-alkali catalyzed mesoporous bioactive glass ...
15056878 - L-ascorbic acid microencapsulated with polyacylglycerol monostearate for milk fortifica...
4295868 - Mass spectrometry of derivatives of cyclopropene fatty acids.
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Biochemistry. Biokhimii͡a     Volume:  75     ISSN:  1608-3040     ISO Abbreviation:  Biochemistry Mosc.     Publication Date:  2010 Jun 
Date Detail:
Created Date:  2010-07-19     Completed Date:  2010-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0376536     Medline TA:  Biochemistry (Mosc)     Country:  United States    
Other Details:
Languages:  eng     Pagination:  759-68     Citation Subset:  IM    
Institute of Physiology, Komi Science Center, Syktyvkar, Russia.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anticoagulants / chemistry*,  pharmacology
Magnetic Resonance Spectroscopy
Pectins / chemical synthesis,  chemistry*
Spectrophotometry, Infrared
Sulfonic Acids / chemistry
Sulfur / chemistry*
Reg. No./Substance:
0/Anticoagulants; 0/Pectins; 0/Sulfonic Acids; 0/bergenan BC; 0/lemnan; 7704-34-9/Sulfur; 7790-94-5/chlorosulfonic acid; 9046-38-2/polygalacturonic acid

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  The Internal Domain of Hordeivirus Movement Protein TGB1 Forms in vitro Filamentous Structures.
Next Document:  Purification of Core Enzyme of Escherichia coli RNA Polymerase by Affinity Chromatography.