Document Detail

Synthesis and salvage of purines during cellular morphogenesis of Myxococcus xanthus.
MedLine Citation:
PMID:  101526     Owner:  NLM     Status:  MEDLINE    
Intact cells of Myxococcus xanthus were examined for de novo purine synthesis and salvage utilization. The cellular uptake rates of radioactive glycine (de novo purine precursor), adenine, and guanine were measured, and thin-layer chromatography and radioautography were used to examine cell extracts for de novo synthesized purine nucleotides. Intact vegatative cells, glycerol-induced myxospores, and germinating cells of M. xanthus CW-1 were able to carry out de novo purine and salvage synthesis. Germinating cells and glycerol-induced myxospores were metabolically more active or as active as vegetative cells with respect to purine anabolism. We conclude that M. xanthus is capable of synthesizing purine nucleotides and salvaging purines throughout the glycerol version of its life cycle.
W C Tsai; C A Westby
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of bacteriology     Volume:  136     ISSN:  0021-9193     ISO Abbreviation:  J. Bacteriol.     Publication Date:  1978 Nov 
Date Detail:
Created Date:  1979-01-24     Completed Date:  1979-01-24     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985120R     Medline TA:  J Bacteriol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  582-7     Citation Subset:  IM    
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MeSH Terms
Adenine / metabolism*
Adenosine Triphosphate / biosynthesis*
Glycine / metabolism*
Guanine / metabolism*
Myxococcales / cytology,  metabolism*,  physiology
Spores, Bacterial / metabolism
Reg. No./Substance:
56-40-6/Glycine; 56-65-5/Adenosine Triphosphate; 73-24-5/Adenine; 73-40-5/Guanine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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