Document Detail

Synthesis of placental proteins by the human placenta perfused in vitro. Preliminary report.
MedLine Citation:
PMID:  2427389     Owner:  NLM     Status:  MEDLINE    
Fresh human placental tissue from deliveries at term was perfused in closed circulation on both the maternal and fetal side. At given times during the 4-hour perfusion period, the amount of human chorionic gonadotropin, human placental lactogen, pregnancy-specific beta 1-glycoprotein and pregnancy-associated plasma protein A was determined in the perfusing buffer. These placental proteins were also quantified in the placental tissue before and after perfusion. Calculations showed that all placentae (n = 3) were able to synthesize all 4 proteins tested.
N A Bersinger; H Schneider; P J Keller
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Publication Detail:
Type:  In Vitro; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gynecologic and obstetric investigation     Volume:  22     ISSN:  0378-7346     ISO Abbreviation:  Gynecol. Obstet. Invest.     Publication Date:  1986  
Date Detail:
Created Date:  1986-10-01     Completed Date:  1986-10-01     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  7900587     Medline TA:  Gynecol Obstet Invest     Country:  SWITZERLAND    
Other Details:
Languages:  eng     Pagination:  47-51     Citation Subset:  IM    
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MeSH Terms
Chorionic Gonadotropin / biosynthesis
Placenta / metabolism*
Placental Hormones / biosynthesis*
Placental Lactogen / biosynthesis
Pregnancy-Associated Plasma Protein-A / biosynthesis
Pregnancy-Specific beta 1-Glycoproteins / biosynthesis
Reg. No./Substance:
0/Chorionic Gonadotropin; 0/Placental Hormones; 0/Pregnancy-Specific beta 1-Glycoproteins; 9035-54-5/Placental Lactogen; EC 3.4.24.-/Pregnancy-Associated Plasma Protein-A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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