Document Detail


Synthesis of phosphonamidate peptides by Staudinger reactions of silylated phosphinic acids and esters.
MedLine Citation:
PMID:  20830364     Owner:  NLM     Status:  In-Process    
Abstract/OtherAbstract:
The Staudinger reaction of unprotected azido-peptides with silylated phosphinic acids and esters on the solid support offers a straightforward acid-free entry to different phosphonamidate peptide esters or acids under mild conditions in high purity and yield.
Authors:
Ina Wilkening; Giuseppe del Signore; Christian P R Hackenberger
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2010-09-07
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  47     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  England    
Other Details:
Languages:  eng     Pagination:  349-51     Citation Subset:  IM    
Affiliation:
Freie Universität Berlin, Institut für Chemie und Biochemie, Takustr. 3, 14195 Berlin, Germany.
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