| Synthesis of hollow hybrid hydroxyapatite microspheres based on chitosan-poly(acrylic acid) microparticles. | |
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MedLine Citation:
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PMID: 19372618 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Core-template-free hybrid hydroxyapatite (HA) hollow microspheres based on a chitosan-poly acrylic acid (CS-PAA) complex were prepared. The amine groups on chitosan can interact with the carboxyl groups of poly(acrylic acid) to form hollow microspheres. The hollow HA microspheres of about 1.0 microm are obtained by heterogeneous nucleation of HA on CS-PAA hollow spheres. Gelatin (Gel), acting as a novel cross-link agent, is introduced to bind the spheres of CS-PAA and HA. The forming mechanism of hollow spheres and the influencing factors on the size of microspheres are investigated. In addition, the role of Gel is elucidated in the forming process of the hollow hybrid sphere. |
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Authors:
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Haibin Zhang; Kechao Zhou; Zhiyou Li; Suping Huang |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-04-17 |
Journal Detail:
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Title: Biomedical materials (Bristol, England) Volume: 4 ISSN: 1748-605X ISO Abbreviation: Biomed Mater Publication Date: 2009 Jun |
Date Detail:
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Created Date: 2009-06-05 Completed Date: 2009-08-20 Revised Date: 2010-03-11 |
Medline Journal Info:
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Nlm Unique ID: 101285195 Medline TA: Biomed Mater Country: England |
Other Details:
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Languages: eng Pagination: 031002 Citation Subset: IM |
Affiliation:
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State Key Laboratory of Powder Metallurgy, Central South University, Changsha, 410083, People's Republic of China. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acrylic Resins
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chemistry* Biocompatible Materials / chemistry* Chitosan / chemistry* Computer Simulation Durapatite / chemistry* Microspheres Models, Chemical* Models, Molecular |
| Chemical | |
Reg. No./Substance:
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0/Acrylic Resins; 0/Biocompatible Materials; 1306-06-5/Durapatite; 9003-01-4/carbopol 940; 9012-76-4/Chitosan |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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