Document Detail


Synthesis of a fluorescently tagged sialic acid analogue useful for live-cell imaging.
MedLine Citation:
PMID:  22914432     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A cytidine 5'-monophosphate (CMP)-sialic acid analogue carrying a fluorescent reporter group, an inhibitor of sialyltransferase, was synthesised in order to investigate glycan synthesis events in cells. The compound was found to be a substrate of a CMP-sialic acid transporter, and specific Golgi vesicles were visualised in the cells.
Authors:
Katsuhiko Suzuki; Atsuko Ohtake; Yukishige Ito; Osamu Kanie
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-23
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  Chem. Commun. (Camb.)     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-23     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
RIKEN Advanced Science Institute (ASI), Wako, Saitama 351-0198, Japan.
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