Document Detail

Synthesis of fluorescent molecular probes specific for the receptor of blepharismone, a mating-inducing pheromone of the ciliate Blepharisma japonicum.
MedLine Citation:
PMID:  17189699     Owner:  NLM     Status:  MEDLINE    
Blepharismone (gamone 2) is a mating-inducing pheromone of the ciliate Blepharisma japonicum. N-Pyrenylbutyryl-blepharismone and N-biphenylacetyl-blepharismone, which are fluorescent derivatives of blepharismone, were synthesized as molecular probes for the gamone 2 receptor. Further, we proved that they have inhibitory activities against the blepharismone-induced monotypic pairing of B. japonicum.
Yoshiyuki Uruma; Mayumi Sugiura; Terue Harumoto; Yoshinosuke Usuki; Hideo Iio
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2006-12-14
Journal Detail:
Title:  Bioorganic & medicinal chemistry     Volume:  15     ISSN:  0968-0896     ISO Abbreviation:  Bioorg. Med. Chem.     Publication Date:  2007 Feb 
Date Detail:
Created Date:  2007-01-17     Completed Date:  2007-04-03     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9413298     Medline TA:  Bioorg Med Chem     Country:  England    
Other Details:
Languages:  eng     Pagination:  1622-7     Citation Subset:  IM    
Department of Material Science, Graduate School of Science, Osaka City University, Osaka 558-8585, Japan.
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MeSH Terms
Fluorescent Dyes / chemical synthesis*
Hydroxybenzoic Acids / antagonists & inhibitors*,  chemical synthesis
Protozoan Proteins / antagonists & inhibitors
Receptors, Pheromone / analysis,  antagonists & inhibitors
Sex Attractants / antagonists & inhibitors*
Reg. No./Substance:
0/Fluorescent Dyes; 0/Hydroxybenzoic Acids; 0/Protozoan Proteins; 0/Receptors, Pheromone; 0/Sex Attractants; 51064-22-3/blepharismone

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