| Synthesis of chiral 13C,77Se-labeled selones. | |
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MedLine Citation:
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PMID: 15255756 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Stable isotope-labeled N-acyl selones have been constructed in fewer than four steps from readily available starting materials. Site-specific labeling was achieved using the following synthons: bromo[2-(13)C]acetic acid, [(13)C]formic acid, and elemental (77)Se. These labeled selones have been found to provide unique insights into enolate structure and may be useful in the detection and quantitation of remotely disposed chiral centers in compounds in short supply. |
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Authors:
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Morgane Ollivault-Shiflett; David B Kimball; L A Pete Silks |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: The Journal of organic chemistry Volume: 69 ISSN: 0022-3263 ISO Abbreviation: J. Org. Chem. Publication Date: 2004 Jul |
Date Detail:
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Created Date: 2004-07-16 Completed Date: 2004-09-17 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 2985193R Medline TA: J Org Chem Country: United States |
Other Details:
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Languages: eng Pagination: 5150-2 Citation Subset: IM |
Affiliation:
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Los Alamos National Laboratory, Bioscience Division, the Biotechnology, Spectroscopy, and Isotope Chemistry group (B-SIC), NIH National Stable Isotope Resource, MS E529, Los Alamos, NM 87545, USA. pete-silks@lanl.gov |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Carbon Isotopes Isotopes Magnetic Resonance Spectroscopy Molecular Structure Selenium Compounds / chemistry* |
| Grant Support | |
ID/Acronym/Agency:
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RR 02231/RR/NCRR NIH HHS |
| Chemical | |
Reg. No./Substance:
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0/Carbon Isotopes; 0/Isotopes; 0/Selenium Compounds |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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