Document Detail

Synthesis of a carboxylate functionalized bis-amino acid monomer.
MedLine Citation:
PMID:  19391596     Owner:  NLM     Status:  MEDLINE    
The synthesis of the first functionalized bis-amino acid monomer proAc(2S3S4R) 1 that carries an acetyl side chain is presented. This monomer was incorporated into oligomer 3 and the solution phase structure was determined by using two-dimensional nuclear magnetic resonance. The solution structure confirmed the intended connectivity and stereochemistry of the oligomer. This first functionalized bis-amino acid represents a milestone toward functionalized bis-peptide nanostructures for catalytic, molecular recognition, and nanotechnology applications.
Sharad Gupta; Christian E Schafmeister
Related Documents :
18217746 - Amino acid adsorption on mesoporous materials: influence of types of amino acids, modif...
22381886 - Field enhancement sample stacking for analysis of organic acids in traditional chinese ...
545956 - Laser raman spectroscopy of arylsulphatase b from rat liver.
15348686 - The interaction of dental cements with aqueous solutions of varying ph.
17956236 - The role of 2-hydroxyacyl-coa lyase, a thiamin pyrophosphate-dependent enzyme, in the p...
18166596 - Air pollution, oxidative stress and dietary supplementation: a review.
Publication Detail:
Type:  Journal Article; Research Support, N.I.H., Extramural    
Journal Detail:
Title:  The Journal of organic chemistry     Volume:  74     ISSN:  1520-6904     ISO Abbreviation:  J. Org. Chem.     Publication Date:  2009 May 
Date Detail:
Created Date:  2009-05-08     Completed Date:  2009-07-21     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  2985193R     Medline TA:  J Org Chem     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3652-8     Citation Subset:  IM    
Department of Chemistry, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, USA.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Amides / chemistry
Amino Acids / chemical synthesis*,  chemistry
Carboxylic Acids / chemistry*
Esters / chemistry
Models, Molecular
Molecular Conformation
Solvents / chemistry
Grant Support
Reg. No./Substance:
0/Amides; 0/Amino Acids; 0/Carboxylic Acids; 0/Esters; 0/Solvents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Octahedral HSiCl3 and HSiCl2Me adducts with pyridines.
Next Document:  A minima hopping study of all-atom protein folding and structure prediction.