| Synthesis of bioreducible and acid labile poly(amido amine)s via Michael-addition reactions and their application in gene delivery. | |
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MedLine Citation:
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PMID: 22195836 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Reducible poly(amido amine)s (HPAAs) with acid labile groups have been prepared via Michael addition polymerization. These PAAs are very sensitive to reducing agents such as dithiothreitol (DTT) and glutathione (GSH), and sensitive to pH. The polymers show good condensing property for DNA and good gene transfection efficiency. |
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Authors:
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Zhiqiang Yu; Junjie Yan; Yezi You |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of controlled release : official journal of the Controlled Release Society Volume: 152 Suppl 1 ISSN: 1873-4995 ISO Abbreviation: J Control Release Publication Date: 2011 Nov |
Date Detail:
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Created Date: 2011-12-26 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8607908 Medline TA: J Control Release Country: Netherlands |
Other Details:
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Languages: eng Pagination: e179-81 Citation Subset: IM |
Copyright Information:
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Copyright © 2011. Published by Elsevier B.V. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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