| Synthesis and biological evaluation of dehydroabietic acid derivatives. | |
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MedLine Citation:
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PMID: 19892441 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A series of C18-oxygenated derivatives of dehydroabietic acid were synthesized from commercial abietic acid and evaluated for their cytotoxic, antimycotic, and antiviral activities. |
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Authors:
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Miguel A Gonz?lez; David P?rez-Guaita; Julieth Correa-Royero; Bibiana Zapata; Lee Agudelo; Ana Mesa-Arango; Liliana Betancur-Galvis |
Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-10-13 |
Journal Detail:
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Title: European journal of medicinal chemistry Volume: 45 ISSN: 1768-3254 ISO Abbreviation: Eur J Med Chem Publication Date: 2010 Feb |
Date Detail:
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Created Date: 2010-02-01 Completed Date: 2010-04-29 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0420510 Medline TA: Eur J Med Chem Country: France |
Other Details:
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Languages: eng Pagination: 811-6 Citation Subset: IM |
Copyright Information:
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Copyright 2009 Elsevier Masson SAS. All rights reserved. |
Affiliation:
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Departamento de Qu?mica Org?nica, Universidad de Valencia, E-46100 Burjassot, Valencia, Spain. miguel.a.gonzalez@uv.es |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antifungal Agents / chemical synthesis, chemistry, pharmacology Antineoplastic Agents / chemical synthesis, chemistry, pharmacology Antiviral Agents / chemical synthesis, chemistry, pharmacology Cell Line, Tumor Diterpenes, Abietane / chemical synthesis, chemistry*, pharmacology* Fungi / drug effects Herpesvirus 1, Human / drug effects Humans Hydrophobicity Inhibitory Concentration 50 Microbial Sensitivity Tests |
| Chemical | |
Reg. No./Substance:
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0/Antifungal Agents; 0/Antineoplastic Agents; 0/Antiviral Agents; 0/Diterpenes, Abietane; 1740-19-8/dehydroabietic acid; 514-10-3/abietic acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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