| Synthesis and biological activity of a novel series of 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides. | |
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MedLine Citation:
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PMID: 14971314 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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A series of new 4-[2'-(6'-nitro)benzimidazolyl]benzoyl amino acids and peptides have been synthesized by coupling the 4-[2'-(6'-nitro)benzimidazolyl]benzoic acid with amino acid methyl esters/dipeptides using DCC as the coupling agent. All the synthesized compounds were found to exhibit potent anthelmintic activity along with moderate antimicrobial activity. |
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Authors:
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M Himaja; Rajiv; M V Ramana; Boja Poojary; D Satyanarayana; E V Subrahmanyam; K Ishwar Bhat |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Bollettino chimico farmaceutico Volume: 142 ISSN: 0006-6648 ISO Abbreviation: Boll Chim Farm Publication Date: 2003 Dec |
Date Detail:
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Created Date: 2004-02-19 Completed Date: 2004-03-23 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0372534 Medline TA: Boll Chim Farm Country: Italy |
Other Details:
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Languages: eng Pagination: 450-3 Citation Subset: IM |
Affiliation:
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NGSM Institute of Pharmaceutical Sciences, Nanthoor, Mangalore, India. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Animals Anthelmintics / chemical synthesis*, pharmacology* Anti-Infective Agents / chemical synthesis*, pharmacology* Bacteria / drug effects Benzoates / chemical synthesis*, pharmacology* Helminths Imidazoles / chemical synthesis*, pharmacology* Indicators and Reagents Magnetic Resonance Spectroscopy Mass Spectrometry Microbial Sensitivity Tests Peptides / chemical synthesis*, pharmacology* Spectrophotometry, Infrared |
| Chemical | |
Reg. No./Substance:
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0/Anthelmintics; 0/Anti-Infective Agents; 0/Benzoates; 0/Imidazoles; 0/Indicators and Reagents; 0/Peptides |
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