| Synthesis of biocompatible hybrid magnetic hollow spheres based on encapsulation strategy. | |
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MedLine Citation:
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PMID: 23218330 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A kind of novel magnetic hollow spheres was prepared by encapsulating magnetofluid into polymeric hollow spheres. Polymeric hollow nanospheres were constructed by self-assembly of rod-coil complexes, in which the rod-like segments were formed by inclusion of α-cyclodextrins (α-CD) and grafting poly(ethylene glycol) (PEG) chains of chitosan-graft-PEG (CS-g-PEG). Structural characteristics of CS-g-PEG/α-CD hollow spheres were investigated in detail by NMR, XRD, TEM, etc. Furthermore, those hollow spheres showed a pH responsive property which induced a considerable change of their radius. Magnetofluid was physically entrapped into the empty domain while hollow spheres were formed, it was found that the hollow spheres can encapsulate large quantities of magnetofluid and the encapsulated magnetofluid still possess magnetic responsiveness properties. We expect that this strategy may be served as a novel and more straightforward approach to obtain magnetic hollow spheres for biomedical application. |
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Authors:
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Wei Ha; Hao Wu; Yuan Ma; Min-Min Fan; Shu-Lin Peng; Li-Sheng Ding; Sheng Zhang; Bang-Jing Li |
Publication Detail:
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Type: Journal Article Date: 2012-10-02 |
Journal Detail:
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Title: Carbohydrate polymers Volume: 92 ISSN: 1879-1344 ISO Abbreviation: Carbohydr Polym Publication Date: 2013 Jan |
Date Detail:
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Created Date: 2012-12-10 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8307156 Medline TA: Carbohydr Polym Country: England |
Other Details:
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Languages: eng Pagination: 523-8 Citation Subset: IM |
Copyright Information:
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Copyright © 2012 Elsevier Ltd. All rights reserved. |
Affiliation:
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Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu 610041, China. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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