| Synthesis and anticoagulant activity of a new series of 1,4-dihydropyridine derivatives. | |
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MedLine Citation:
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PMID: 21220179 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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A series of 1,4-dihydropyridine derivatives (1a-g) were prepared from three compounds condensation reaction of ethylacetoacetate, aromatic aldehyde and ammonium hydroxide. A new series of compounds (2a-g) were prepared from compounds (1a-g) via reaction with thiosemicarbazide using the condensation method. The synthesized compounds were confirmed by IR, (1)H NMR, (13)C NMR, mass spectral and elemental analyses. The synthesized compounds (1a-g) and (2a-g) were also screened for anticoagulant properties. |
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Authors:
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R Surendra Kumar; A Idhayadhulla; A Jamal Abdul Nasser; J Selvin |
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Publication Detail:
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Type: Journal Article Date: 2010-12-15 |
Journal Detail:
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Title: European journal of medicinal chemistry Volume: 46 ISSN: 1768-3254 ISO Abbreviation: Eur J Med Chem Publication Date: 2011 Feb |
Date Detail:
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Created Date: 2011-01-25 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 0420510 Medline TA: Eur J Med Chem Country: France |
Other Details:
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Languages: eng Pagination: 804-10 Citation Subset: IM |
Copyright Information:
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Copyright © 2010 Elsevier Masson SAS. All rights reserved. |
Affiliation:
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P.G & Research Dept. of chemistry, Jamal Mohamed College, Tiruchirappalli 620020, Tamil Nadu, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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