| Synthesis of angiotensin I-converting enzyme (ACE)-inhibitory peptides and gamma-aminobutyric acid (GABA) during sourdough fermentation by selected lactic acid bacteria. | |
| | |
MedLine Citation:
|
PMID: 18627167 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
This article aimed at investigating the synthesis of angiotensin I-converting enzyme (ACE)-inhibitory peptides and gamma-aminobutyric acid (GABA) during sourdough fermentation of white wheat, wholemeal wheat, and rye flours. Sourdough lactic acid bacteria, selected previously for proteinase and peptidase activities toward wheat proteins or for the capacity of synthesizing GABA, were used. The highest ACE-inhibitory activity was found by fermenting flour under semiliquid conditions (dough yield 330) and, especially, by using wholemeal wheat flour. Fourteen peptides, not previously reported as ACE-inhibitory, were identified from the water/salt-soluble extract of wholemeal wheat sourdough (IC 50 0.19-0.54 mg/mL). The major part of the identified peptides contained the well-known antihypertensive epitope VAP. The synthesis of GABA increased when the dough yield was decreased to 160. The highest synthesis of GABA (258.71 mg/kg) was found in wholemeal wheat sourdough. |
| | |
Authors:
|
C G Rizzello; A Cassone; R Di Cagno; M Gobbetti |
Related Documents
:
|
1407267 - Comparative study between 4-aminobutyrate-2-oxoglutarate aminotransferase (gaba-t) from... 490547 - Structural analogues of l-glutamic acid gamma-(4-hydroxyanilide) and gamma-(3,4-dihydro... 9136807 - Taurine in rat posterior pituitary: localization in astrocytes and selective release by... 9227407 - Volume regulation in nih/3t3 cells not expressing p-glycoprotein. i. regulatory volume ... 16977387 - Synthesis and characterization of cholesterol-poly(ethylene glycol)-poly(d,l-lactic aci... 3664957 - Effect of butyric acid on 12-o-tetradecanoylphorbol-13-acetate-(tpa) induced mouse skin... |
Publication Detail:
|
Type: Journal Article Date: 2008-07-16 |
Journal Detail:
|
Title: Journal of agricultural and food chemistry Volume: 56 ISSN: 1520-5118 ISO Abbreviation: J. Agric. Food Chem. Publication Date: 2008 Aug |
Date Detail:
|
Created Date: 2008-08-20 Completed Date: 2008-10-06 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0374755 Medline TA: J Agric Food Chem Country: United States |
Other Details:
|
Languages: eng Pagination: 6936-43 Citation Subset: IM |
Affiliation:
|
Department of Plant Protection and Applied Microbiology, University of Bari, 70126 Bari, Italy. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amino Acid Sequence Angiotensin-Converting Enzyme Inhibitors / metabolism*, pharmacology Bread / analysis* Chromatography, High Pressure Liquid Fermentation* Lactobacillus / metabolism* Molecular Sequence Data Peptide Biosynthesis* Peptides / chemistry, isolation & purification, pharmacology gamma-Aminobutyric Acid / analysis, biosynthesis* |
| Chemical | |
Reg. No./Substance:
|
0/Angiotensin-Converting Enzyme Inhibitors; 0/Peptides; 56-12-2/gamma-Aminobutyric Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Differences in odor-active compounds of trincadeira wines obtained from five different clones.
Next Document: Structure and functional properties of sorghum starches differing in amylose content.