| Synthesis of (S)-ibuprofen via enantioselective degradation of racemic ibuprofen with an isolated yeast, Trichosporon cutaneum KPY 30802, in an interface bioreactor. | |
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MedLine Citation:
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PMID: 16232996 Owner: NLM Status: PubMed-not-MEDLINE |
Abstract/OtherAbstract:
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An interface bioreactor was used for the enantioselective degradation of (RS)-ibuprofen (IBU). An isolated yeast, Trichosporon cutaneum KPY 30802, preferentially degraded (R)-IBU to accumulate (S)-isomer. The addition of hydroquinone (10 mM) into a hydrophilic carrier was effective for the elevation of enantiomeric excess and the repression of excess degradation of (S)-IBU (E value, 9.3). |
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Authors:
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J Tanaka; S Oda; H Ohta |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of bioscience and bioengineering Volume: 91 ISSN: 1389-1723 ISO Abbreviation: J. Biosci. Bioeng. Publication Date: 2001 |
Date Detail:
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Created Date: 2005-10-19 Completed Date: 2005-11-01 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 100888800 Medline TA: J Biosci Bioeng Country: Japan |
Other Details:
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Languages: eng Pagination: 314-5 Citation Subset: - |
Affiliation:
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Technical Research Laboratory, Kansai Paint Co. Ltd., 4-17-1 Higashi-Yawata, Hiratsuka, Kanagawa 254-8562, Japan. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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