| Synthesis of (S)-2-Boc-Amino-8-(R)-(tert-butyldimethylsilanyloxy) decanoic acid, a Precursor to the Unusual Amino Acid Residue of the Anticancer Agent Microsporin B. | |
| | |
MedLine Citation:
|
PMID: 21984850 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
(S)-2-Boc-Amino-8-(R)-(tert-butyldimethylsilanyloxy) decanoic acid, the Boc-protected precursor of an unusual amino acid residue for the synthesis of microsporin B, was synthesized. The key steps include a Suzuki coupling followed by asymmetric homogeneous hydrogenation. |
| | |
Authors:
|
Wenxin Gu; Richard B Silverman |
Publication Detail:
|
Type: JOURNAL ARTICLE |
Journal Detail:
|
Title: Tetrahedron letters Volume: 52 ISSN: 0040-4039 ISO Abbreviation: - Publication Date: 2011 Oct |
Date Detail:
|
Created Date: 2011-10-10 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 2984819R Medline TA: Tetrahedron Lett Country: - |
Other Details:
|
Languages: ENG Pagination: 5438-5440 Citation Subset: - |
Affiliation:
|
Department of Chemistry, Department of Molecular Biosciences, Chemistry of Life Processes Institute, Center for Molecular Innovation and Drug Discovery, Northwestern University, Evanston, IL, 60208-3113. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
| Grant Support | |
ID/Acronym/Agency:
|
R41 CA116971-01//NCI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Interactions of a replication initiator with histone H1-like proteins remodel the condensed mitochon...
Next Document: Factors involved in the distribution pattern of ciliates in the water column of a transparent alpine...