| Synthesis of axially chiral amino acid and amino alcohols via additive-ligand-free Pd-catalyzed domino coupling reaction and subsequent transformations of the product amidoaza[5]helicene. | |
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MedLine Citation:
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PMID: 20839825 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Novel optically active axially chiral amino acid and amino alcohols have been synthesized efficiently via lactam ring-opening, with the aid of an optically active alcohol, amidoaza[5]helicene 5, which has been readily prepared by an additive-ligand-free Pd catalyzed domino coupling reaction in a single step. The stereostructures of these chiral molecules have also been clarified. |
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Authors:
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Takumi Furuta; Junya Yamamoto; Yuki Kitamura; Ayano Hashimoto; Hyuma Masu; Isao Azumaya; Toshiyuki Kan; Takeo Kawabata |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: The Journal of organic chemistry Volume: 75 ISSN: 1520-6904 ISO Abbreviation: J. Org. Chem. Publication Date: 2010 Oct |
Date Detail:
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Created Date: 2010-10-08 Completed Date: 2011-01-25 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 2985193R Medline TA: J Org Chem Country: United States |
Other Details:
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Languages: eng Pagination: 7010-3 Citation Subset: IM |
Affiliation:
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Institute for Chemical Research, Kyoto University, Uji 611-0011, Kyoto, Japan. furuta@fos.kuicr.kyoto-u.ac.jp |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Amides
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chemistry* Amino Acids / chemical synthesis*, chemistry Amino Alcohols / chemical synthesis*, chemistry Ligands Molecular Structure Organometallic Compounds / chemistry* Palladium / chemistry* Stereoisomerism |
| Chemical | |
Reg. No./Substance:
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0/Amides; 0/Amino Acids; 0/Amino Alcohols; 0/Ligands; 0/Organometallic Compounds; 7440-05-3/Palladium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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