Document Detail

Synthesis of the ABH rings of ecteinascidin 597 using a connective Pummerer-type cyclisation.
MedLine Citation:
PMID:  21863175     Owner:  NLM     Status:  Publisher    
A connective Pummerer-type cyclisation involving a cysteine derivative and an N-benzyl glyoxamide 3 has been applied in an asymmetric synthesis of the protected ABH rings 2 of the antitumour and antimicrobial natural product ecteinascidin 597.
Laura H S Smith; Trung Thanh Nguyen; Helen F Sneddon; David J Procter
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-24
Journal Detail:
Title:  Chemical communications (Cambridge, England)     Volume:  -     ISSN:  1364-548X     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9610838     Medline TA:  Chem Commun (Camb)     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
School of Chemistry, University of Manchester, Oxford Road, Manchester, M13 9PL, UK.
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