Document Detail


Synthesis of 5-amino-oxazole-4-carboxylates from alpha-chloroglycinates.
MedLine Citation:
PMID:  20698488     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Aluminum-based Lewis acids are effective promoters of the condensation of alpha-chloroglycinates with isonitriles or with cyanide ion, leading to the formation of 5-amino-oxazoles.
Authors:
Jianmin Zhang; Pierre-Yves Coqueron; Jean-Pierre Vors; Marco A Ciufolini
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Organic letters     Volume:  12     ISSN:  1523-7052     ISO Abbreviation:  Org. Lett.     Publication Date:  2010 Sep 
Date Detail:
Created Date:  2010-08-27     Completed Date:  2010-12-02     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  100890393     Medline TA:  Org Lett     Country:  United States    
Other Details:
Languages:  eng     Pagination:  3942-5     Citation Subset:  IM    
Affiliation:
Department of Chemistry, University of British Columbia, 2036 Main Mall, Vancouver, BC V6T 1Z1, Canada.
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MeSH Terms
Descriptor/Qualifier:
Aluminum / chemistry
Amines / chemical synthesis*,  chemistry
Carboxylic Acids / chemical synthesis*,  chemistry
Combinatorial Chemistry Techniques
Esters
Glycine / analogs & derivatives*,  chemistry*
Hydrocarbons, Chlorinated / chemistry*
Lewis Acids / chemistry
Molecular Structure
Nitriles / chemistry
Oxazoles / chemical synthesis*,  chemistry
Stereoisomerism
Grant Support
ID/Acronym/Agency:
//Canadian Institutes of Health Research
Chemical
Reg. No./Substance:
0/Amines; 0/Carboxylic Acids; 0/Esters; 0/Hydrocarbons, Chlorinated; 0/Lewis Acids; 0/Nitriles; 0/Oxazoles; 56-40-6/Glycine; 7429-90-5/Aluminum

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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