| Synthesis of 2-hydroxy acid from 2-amino acid by Clostridium butyricum. | |
| | |
MedLine Citation:
|
PMID: 9873747 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Cultures of Clostridium butyricum type strain in synthetic medium supplemented with various L-2-amino acids revealed the presence of the corresponding 2-hydroxy acid. This metabolite is able to produce the polyester poly(2-hydroxyalkanoic acid). The bioconversion is not stereoselective since D-2-amino acids were also converted. Chiral GC analysis demonstrated that only D-enantiomer is formed from L-leucine. |
| | |
Authors:
|
N Khelifa; M J Butel; A Rimbault |
Related Documents
:
|
15979187 - Cisplatin delivery from poly(acrylic acid-co-methyl methacrylate) microparticles. 17415487 - Intermediate temperature proton conductors for pem fuel cells based on phosphonic acid ... 18163537 - Synthesis, characterization, antitumor activity of pluronic mimicking copolymer micelle... 10675707 - Study on glycolic acid delivery by liposomes and microspheres. 12839787 - Ingestion of salmonella enterica serotype poona by a free-living mematode, caenorhabdit... 1825997 - Ascorbic acid regeneration in chromaffin granules. in situ kinetics. |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Bioorganic & medicinal chemistry letters Volume: 8 ISSN: 0960-894X ISO Abbreviation: Bioorg. Med. Chem. Lett. Publication Date: 1998 Dec |
Date Detail:
|
Created Date: 1999-01-21 Completed Date: 1999-01-21 Revised Date: 2000-12-18 |
Medline Journal Info:
|
Nlm Unique ID: 9107377 Medline TA: Bioorg Med Chem Lett Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 3429-34 Citation Subset: IM |
Affiliation:
|
Laboratoire de Microbiologie, Unité Microbiologie Anaérobie, Faculté des Sciences Pharmaceutiques et Biologiques de Paris, Université René Descartes, France. nasser.khelifa@pharmacie.univ-paris5.fr |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Amino Acids
/
metabolism* Clostridium / metabolism* Hydroxy Acids / metabolism* Molecular Conformation |
| Chemical | |
Reg. No./Substance:
|
0/Amino Acids; 0/Hydroxy Acids |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Synthesis of 4'-epi-iodo-4'-deoxy-daunorubicin, a potential cancer radiotherapeutic agent.
Next Document: Synthesis and evaluation of a new inhibitor of phosphoglucose isomerases: the enediolate analogue 5-...