| Synthesis of 1,2,4-triazole derivatives containing benzothiazoles as pharmacologically active molecule. | |
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MedLine Citation:
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PMID: 21714763 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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In attempt to make significant pharmacologically active molecule, we report here the synthesis and in vitro antimicrobial and antitubercular activity of various series of 3-(3-pyridyl)-5-(4-nitrophenyl)-4-(N-substituted-1,3-benzothiazol-2-amino)-4H-1,2,4-triazole. The antimicrobial activity of title compounds were examined against two Gram-positive bacteria (Staphylococcus aureus, Streptococcus pyogenes), two Gram-negative bacteria (Escherichia coli, Pseudomonas aeruginosa), and three fungi (Candida albicans, Aspergillus niger, Aspergillus clavatus) using the broth microdilution method and antitubercular activity H(37)Rv using Lowenstein-Jensen agar method. |
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Authors:
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Navin B Patel; Imran H Khan |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of enzyme inhibition and medicinal chemistry Volume: 26 ISSN: 1475-6374 ISO Abbreviation: J Enzyme Inhib Med Chem Publication Date: 2011 Aug |
Date Detail:
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Created Date: 2011-06-30 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101150203 Medline TA: J Enzyme Inhib Med Chem Country: England |
Other Details:
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Languages: eng Pagination: 527-34 Citation Subset: IM |
Affiliation:
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Department of Chemistry, Veer Narmad South Gujarat University, Surat, Gujarat, India. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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