Document Detail


Syntheses of new androstane brassinosteroids with 17beta-ester groups--butyrates, heptafluorobutyrates, and laurates.
MedLine Citation:
PMID:  15921713     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
New androstane brassinosteroids with 17beta-ester groups - butyrates, heptafluorobutyrates, and laurates (4-18) - were prepared. Brassinolide activity was evaluated using both the bean second internode bioassay and the rice lamina inclination test. Brassinosteroid 16 was found to be the most active by the bean second internode bioassay. This activity in the bean second internode bioassay corresponded with the field yield, while the RLIT bioassay does not.
Authors:
Miroslav Sísa; Jaroslava Hnilicková; Jana Swaczynová; Ladislav Kohout
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Steroids     Volume:  70     ISSN:  0039-128X     ISO Abbreviation:  Steroids     Publication Date:  2005 Oct 
Date Detail:
Created Date:  2005-08-22     Completed Date:  2005-12-15     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0404536     Medline TA:  Steroids     Country:  United States    
Other Details:
Languages:  eng     Pagination:  755-62     Citation Subset:  IM    
Affiliation:
Institute of Organic Chemistry and Biochemistry, Academy of Sciences of the Czech Republic, 166 10 Prague 6, Czech Republic.
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MeSH Terms
Descriptor/Qualifier:
Androstanes / chemical synthesis*,  chemistry,  pharmacology
Biological Assay
Butyrates / chemistry*
Cholestanols / chemical synthesis*,  chemistry,  pharmacology
Esterification
Fluorocarbons / chemistry*
Laurates / chemistry*
Magnetic Resonance Spectroscopy
Molecular Structure
Oryza sativa / drug effects,  growth & development
Phaseolus / drug effects,  growth & development
Steroids, Heterocyclic / chemical synthesis*,  chemistry,  pharmacology
Structure-Activity Relationship
Chemical
Reg. No./Substance:
0/Androstanes; 0/Butyrates; 0/Cholestanols; 0/Fluorocarbons; 0/Laurates; 0/Steroids, Heterocyclic; 375-22-4/perfluorobutyric acid; 72962-43-7/brassinolide

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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