Document Detail

Synovial chondromatosis: clonal chromosome changes provide further evidence for a neoplastic disorder.
MedLine Citation:
PMID:  9737798     Owner:  NLM     Status:  MEDLINE    
Synovial chondromatosis is a rare lesion, which is still believed by most authors to be reactive rather than neoplastic. We report on a case of synovial chondromatosis with clonal chromosomal changes [43,XX,der (1) t (1;13) (p21-22;q21),-6,-13,-14, add(21) (q21)]. The presence of clonal chromosomal changes in this and in three previously reported cases suggests that synovial chondromatosis is a true neoplastic lesion.
R Sciot; P Dal Cin; J Bellemans; I Samson; H Van den Berghe; B Van Damme
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Virchows Archiv : an international journal of pathology     Volume:  433     ISSN:  0945-6317     ISO Abbreviation:  Virchows Arch.     Publication Date:  1998 Aug 
Date Detail:
Created Date:  1998-09-25     Completed Date:  1998-09-25     Revised Date:  2005-11-16    
Medline Journal Info:
Nlm Unique ID:  9423843     Medline TA:  Virchows Arch     Country:  GERMANY    
Other Details:
Languages:  eng     Pagination:  189-91     Citation Subset:  IM    
Department of Pathology, University of Leuven, Belgium.
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MeSH Terms
Chondromatosis, Synovial / genetics*,  pathology
Chromosome Aberrations*
Chromosomes, Human, Pair 1
Chromosomes, Human, Pair 13
Chromosomes, Human, Pair 14
Chromosomes, Human, Pair 21
Chromosomes, Human, Pair 6
Middle Aged
Neoplasms / genetics*
Translocation, Genetic

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