Document Detail


Synergistic growth promoting action of L-cysteine and nitrogen upon Hymenolepis diminuta cysticercoids in vitro.
MedLine Citation:
PMID:  1003285     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Development in vitro of cysticercoids of the cestode Hymenolepis diminuta in the presence of L-cysteine proceeded twice as rapidly under 100% nitrogen as it did with air as the gas phase. No growth was obtained with the following: D-cysteine, L-cysteine methyl ester, S-aminoethyl cysteine, L-cystine, glutathione (reduced), L-methionine, D-pantothenic acid, taurine, or thioglycolic acid; limited growth only was obtained with ascorbic acid and dithiothreitol. Homocysteine or coenzyme A was as effective as L-cysteine in stimulating the complete development of oncospheres to cysticercoids. Experiments with 14C-L-cysteine indicated that L-cysteine was perhaps incorporated into the organisms.
Authors:
M Voge; J Jaffe; D A Bruckner; E Meymarian
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Journal of parasitology     Volume:  62     ISSN:  0022-3395     ISO Abbreviation:  J. Parasitol.     Publication Date:  1976 Dec 
Date Detail:
Created Date:  1977-02-16     Completed Date:  1977-02-16     Revised Date:  2003-11-14    
Medline Journal Info:
Nlm Unique ID:  7803124     Medline TA:  J Parasitol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  951-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Animals
Ascorbic Acid / pharmacology
Cestoda / growth & development*
Coenzyme A / pharmacology
Cysteine / pharmacology*
Drug Synergism
Hymenolepis / drug effects,  growth & development*
Nitrogen / pharmacology*
Pantothenic Acid / pharmacology
Chemical
Reg. No./Substance:
50-81-7/Ascorbic Acid; 52-90-4/Cysteine; 7727-37-9/Nitrogen; 79-83-4/Pantothenic Acid; 85-61-0/Coenzyme A

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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