| Synergistic Effects of Low-Intensity Exercise Conditioning and β-Blockade on Cardiovascular and Autonomic Adaptation in Pre- and Postmenopausal Women With Hypertension. | |
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MedLine Citation:
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PMID: 23034540 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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The effects of a 12-week low-intensity exercise conditioning program (walking) on blood pressure (BP), heart rate (HR), rate- pressure product (RPP), and cardiac autonomic function were measured in 40 sedentary women with hypertension. Women were assigned to either an exercise group (n = 20) or a control group (n = 20), matched for β-blockade treatment. They underwent testing at the beginning and at the end of the 12-week study period in three conditions: supine rest, standing, and low-intensity steady state exercise. The exercise group participated in a 12-week, low-intensity walking program, while the control group continued with usual sedentary activity. Compared with the control group, women in the exercise group showed reductions in systolic and diastolic BP and RPP (i.e., the estimated cardiac workload). β-Blockers increased baroreflex sensitivity and lowered BP and HR in all participants; however, those in the exercise group showed the effects of both treatments: a greater reduction in HR and RPP. The combination of exercise training and β-blockade produces cardiac and autonomic adaptations that are not observed with either treatment alone, suggesting that β-blockade enhances the conditioning effects of low-intensity exercise in women with hypertension. |
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Authors:
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Catherine L Goldie; C Ann Brown; Sylvia M J Hains; Joel L Parlow; Richard Birtwhistle |
Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-10-2 |
Journal Detail:
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Title: Biological research for nursing Volume: - ISSN: 1552-4175 ISO Abbreviation: Biol Res Nurs Publication Date: 2012 Oct |
Date Detail:
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Created Date: 2012-10-4 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9815758 Medline TA: Biol Res Nurs Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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School of Nursing, Queen's University, Kingston, Canada. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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