| Synergism between Trichuris suis and the microbial flora of the large intestine causing dysentery in pigs. | |
| | |
MedLine Citation:
|
PMID: 1167536 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The role of the microbial flora of the large intestine in experimental Trichuris suis infection was studied by comparing the clinical syndrome in conventionally reared (CR) pigs, specific pathogen-free pigs, and gnotobiotic pigs. Thedisease in CR pigs was characterized by a severe mucohemorrhagic enteritis; in contrast, a mild catarrhal enteritis was observed in specific pathogen-free and gnotobiotic pigs. Spirochaetes and vibrio-like organisms were observed only in CR pigs and increased during the clinical phase of the disease. The clinical syndrome was not transmitted by oral administration of intestinal or fecal material from infected CR pigs to CR pigs free of T. suis. Smaller numbers of T. suis produced diarrhea in CR pigs and significantly reduced the growth rates of infected animals; clinical signs and the reduction in growth rate was prevented by incorporating an antibacterial substance (dimetridazole) in the food. Although clinical trichuriasis closely resembles swin dysentery, the two syndromes seem to be distinct. The present results suggest that a microbial component acts synergistically with T. suis to produce the severe clinical syndrome in CR pigs, but identification of the microbial component and the mechanism by which clinical signs are produced await further studies of the bacterial flora of the large intestine of pigs. |
| | |
Authors:
|
J M Rutter; R J Beer |
Related Documents
:
|
19524716 - Waardenburg syndrome with extended aganglionosis: report of 3 new cases. 8322816 - Mild mandibulofacial dysostosis in a child with a deletion of 3p. 7136506 - Selective loss of small myelinated and unmyelinated fibers in shy-drager syndrome. 19279516 - Rapunzel syndrome-a rare cause of multiple jejunal intussusception. 18173416 - Nodular scleritis and sweet's syndrome. 23657056 - A case of simultaneous occurrence of marine - lenhart syndrome and a papillary thyroid ... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Infection and immunity Volume: 11 ISSN: 0019-9567 ISO Abbreviation: Infect. Immun. Publication Date: 1975 Feb |
Date Detail:
|
Created Date: 1975-05-09 Completed Date: 1975-05-09 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 0246127 Medline TA: Infect Immun Country: UNITED STATES |
Other Details:
|
Languages: eng Pagination: 395-404 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Bacteria / isolation & purification Dysentery / transmission, veterinary* Enteritis / pathology Feces / microbiology Female Germ-Free Life Intestine, Large / immunology, parasitology Lactobacillus / isolation & purification Larva Nitroimidazoles / therapeutic use Ovum Parasite Egg Count Spirochaeta / immunology*, isolation & purification Streptococcus / isolation & purification Swine Swine Diseases / immunology* Trichuriasis / drug therapy Trichuris / immunology* Vibrio / immunology*, isolation & purification |
| Chemical | |
Reg. No./Substance:
|
0/Nitroimidazoles |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Failure of injected growth hormone to increase plasma glucose and insulin concentration in the puppy...
Next Document: Prostatic effects of a nonsteroidal antiandrogen.