| Synergic Effect of Photodynamic Therapy with Methylene Blue and Surfactants in the Inhibition of Candida albicans. | |
| | |
MedLine Citation:
|
PMID: 23187768 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
|
Photodynamic therapy (PDT) has been originally developed for the treatment of cancer, but it has been successfully employed in the treatment of infectious diseases, including fungal infections. Surfactants are amphiphilic compounds that also have antifungal properties. The present work demonstrates the synergic effect of PDT with methylene blue (MB) and LED combined with four different surfactants in the killing of Candida albicans. Subinhibitory concentrations of CTAC, HPS, SDS and Triton X-100 were tested with MB PDT. The combined therapies proved to be more efficient than PDT or surfactants separately. The best results were obtained with CTAC and HPS and PDT with MB at the concentration of 32 μg/mL. In conclusion, the combination of surfactants and PDT is an alternative antifungal treatment that can achieve more effective performance with minimal discomfort to the patient. |
| | |
Authors:
|
Juliana Pereira Lyon; Rafael Reis Rezende; Mariana Penido Rabelo; Carlos José de Lima; Leonardo Marmo Moreira |
Related Documents
:
|
2408418 - Condylomata acuminata in women: the effect of concomitant genital infection on response... 23666548 - Nervous system lyme disease: diagnosis and treatment. 22629178 - Impacts of horticultural mineral oils and two insecticide practices on population fluct... 18475368 - Animal models of ascending genital-tract infection in pregnancy. 20516558 - Short hairpin rnas specific to human cytomegalovirus terminase subunit pul89 prevent vi... 1195268 - Chlamydiosis in a beef herd. |
Publication Detail:
|
Type: JOURNAL ARTICLE Date: 2012-11-28 |
Journal Detail:
|
Title: Mycopathologia Volume: - ISSN: 1573-0832 ISO Abbreviation: Mycopathologia Publication Date: 2012 Nov |
Date Detail:
|
Created Date: 2012-11-28 Completed Date: - Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 7505689 Medline TA: Mycopathologia Country: - |
Other Details:
|
Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
|
Departamento de Ciências Naturais, Universidade Federal de São João Del Rei, São João Del Rei, MG, Brazil, julianalyon@yahoo.com.br. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
|
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Detection of single-nucleotide polymorphisms based on the formation of an electron-transfer impeding...
Next Document: Treatment of Primary Systemic Amyloidosis (AL): Role of Intensive and Standard Therapy.