Document Detail


Syndromology: an updated conceptual overview. VIII. Deformations and disruptions.
MedLine Citation:
PMID:  2110957     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A deformation is an abnormal form or position of the body caused by nondisruptive mechanical forces. Clubfoot, congenital hip dislocation, and infantile mandibular asymmetry (not based on mandibular malformation) serve as examples. The musculoskeletal system is involved in almost all deformations. Various disturbances of intrauterine movement are the usual causes and commonly occur during the fetal period. Causes may be mechanical or malformational. The former includes first pregnancies, small maternal size, uterine malformations and tumors, and amnionic rupture leading to oligohydramnios. Malformational causes usually involve the urogenital system and the central nervous system. A disruption is a morphologic defect of an organ, part of an organ, or a larger region of the body resulting from a breakdown of, or interference with, an originally normal developmental process. Amnionic band disruptions with digital amputations serve as an example. The most recent studies of disruptions and their suggested mechanisms are discussed. Finally, the interrelationships between malformations, deformations, and disruptions are explained.
Authors:
M M Cohen
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  International journal of oral and maxillofacial surgery     Volume:  19     ISSN:  0901-5027     ISO Abbreviation:  Int J Oral Maxillofac Surg     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-06-20     Completed Date:  1990-06-20     Revised Date:  2009-11-19    
Medline Journal Info:
Nlm Unique ID:  8605826     Medline TA:  Int J Oral Maxillofac Surg     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  33-7     Citation Subset:  D; IM    
Affiliation:
Dept. of Oral Biology, Faculty of Dentistry, Dalhousie University, Halifax, Nova Scotia, Canada.
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MeSH Terms
Descriptor/Qualifier:
Abnormalities, Severe Teratoid / embryology
Amniotic Band Syndrome
Amniotic Fluid
Congenital Abnormalities / embryology*,  etiology
Disease*
Female
Fetal Movement
Humans
Infant, Newborn
Posture
Pregnancy
Pregnancy Complications*
Syndrome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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