Document Detail

Syncytial variant of nodular sclerosing Hodgkin's disease. A new clinicopathologic entity.
MedLine Citation:
PMID:  2406009     Owner:  NLM     Status:  MEDLINE    
The clinicopathologic and histopathologic features of an unusual morphologic variant of nodular sclerosing Hodgkin's Disease (HD) termed the syncytial variant has been reported recently. We report eight new cases with this unique morphology, identified by reviewing the histopathology of 58 patients with nodular sclerosing HD treated in our institute between 1982 and 1988. The clinicopathologic and histopathologic data of these cases are reported and we emphasize this new entity and the difficulties encountered in the morphologic diagnosis. All of the eight patients had a difficult initial clinical course, and were in a clinically advanced stage of the disease at the time of diagnosis. We cite a statistical comparison of the clinical features of the different forms of nodular sclerosing HD.
D Ben-Yehuda-Salz; A Ben-Yehuda; A Polliack; N Ron; E Okon
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cancer     Volume:  65     ISSN:  0008-543X     ISO Abbreviation:  Cancer     Publication Date:  1990 Mar 
Date Detail:
Created Date:  1990-03-27     Completed Date:  1990-03-27     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  0374236     Medline TA:  Cancer     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1167-72     Citation Subset:  AIM; IM    
Hematology Department, Hadassah University Hospital, Jerusalem, Israel.
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MeSH Terms
Antibodies, Monoclonal / diagnostic use
Collagen / analysis
Cytoplasm / pathology
Hodgkin Disease / pathology*
Immunoenzyme Techniques
Lymph Nodes / pathology
Middle Aged
Neoplasm Staging
Reg. No./Substance:
0/Antibodies, Monoclonal; 9007-34-5/Collagen

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