| Syncope with cholinesterase inhibitors. | |
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MedLine Citation:
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PMID: 21970087 Owner: NLM Status: In-Process |
Abstract/OtherAbstract:
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Adverse effects of cholinesterase inhibitors used in Alzheimer's disease include cardiac disorders (bradycardia, conduction disorders) that can cause malaise and syncope. A cohort study compared 20 000 patients who received a cholinesterase inhibitor for dementia with a control group of untreated dementia patients. Cholinesterase inhibitor therapy was associated with statistically significant increases in hospitalisations for syncope or bradycardia, pacemaker insertion, and hip fracture. In practice, cholinesterase inhibitors have little more than a placebo effect and do not justify exposing patients to these risks. |
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Authors:
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Prescrire international Volume: 20 ISSN: 1167-7422 ISO Abbreviation: Prescrire Int Publication Date: 2011 Oct |
Date Detail:
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Created Date: 2011-10-05 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9439295 Medline TA: Prescrire Int Country: France |
Other Details:
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Languages: eng Pagination: 240 Citation Subset: T |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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