Document Detail


Synchrony in reaction-diffusion models of morphogenesis: applications to curvature-dependent proliferation and zero-diffusion front waves.
MedLine Citation:
PMID:  19884182     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The paper presents the classical age-dependent approach of the morphogenesis in the framework of the von Foerster equation, in which we introduce a new constraint and study a new feature: (i) the new constraint concerns cell proliferation along the contour lines of the cell density, depending on the local curvature such as it favours the amplification of the concavities (like in the gastrulation process) and (ii) the new feature consists of considering, on the cell density surface, a remarkable line (the null mean Gaussian curvature line), on which the normal diffusion vanishes, favouring local coexistence of diffusing morphogens, metabolites or cells, and hence the auto-assemblages of these entities. Two applications to biological multi-agents systems are studied, gastrulation and feather morphogenesis.
Authors:
Lamia Abbas; Jacques Demongeot; Nicolas Glade
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Philosophical transactions. Series A, Mathematical, physical, and engineering sciences     Volume:  367     ISSN:  1364-503X     ISO Abbreviation:  Philos Trans A Math Phys Eng Sci     Publication Date:  2009 Dec 
Date Detail:
Created Date:  2009-11-03     Completed Date:  2010-03-04     Revised Date:  2013-04-24    
Medline Journal Info:
Nlm Unique ID:  101133385     Medline TA:  Philos Trans A Math Phys Eng Sci     Country:  England    
Other Details:
Languages:  eng     Pagination:  4829-62     Citation Subset:  IM    
Affiliation:
Institut National des Sciences Appliquées Rouen, Laboratoire de Mathématiques de l'INSA EA 3226, Place Emile Blondel BP 08, 76131 Mont-Saint-Aignan, France.
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MeSH Terms
Descriptor/Qualifier:
Animals
Birds
Cell Cycle / physiology*
Feathers / physiology
Gastrulation / physiology
Models, Biological*
Morphogenesis / physiology*
Thermodynamics

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