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Synchronization of Oxygen Delivery With Breathing Pattern for Enhanced Comfort: A Bench Study.
MedLine Citation:
PMID:  22906498     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Oxygen has been widely used for chronic obstructive pulmonary disease (COPD) patients because long-term oxygen therapy (LTOT) can improve survival duration of COPD patients with severe hypoxemia. The typical oxygen delivery methods used for LTOT are continuous flow oxygen (CFO) and demand oxygen delivery (DOD). Currently, DOD is preferred to CFO in oxygen conserving devices because waste of oxygen is substantial in CFO. However, DOD causes discomfort to patients since it abruptly supplies high-flow-rate oxygen during inhalation only. To overcome the drawbacks of CFO and DOD, we developed a novel oxygen delivery method, synchronized demand oxygen delivery (SDOD), which can reduce waste oxygen and patient discomfort. We used the concept of "jerk" from physics, which indicates the rate of change of acceleration, and defined discomfort index (DI) to quantitatively represent the degree of discomfort. To determine the correlation between DI and the actual human feeling of discomfort, we tested subjects' responses to different levels of DI. Moreover, depending on the level of oxygen saving of each method, CFO, DOD, and SDOD regions were identified in a prescription flow rate-supply flow rate plane. A bench study was conducted to experimentally compare the fraction of inspired oxygen (FIO₂) between CFO and SDOD at 20 breaths per minute. The results of this study illustrate that there is a region of compromise between oxygen saving and patient comfort that is filled by SDOD. DI is positively correlated with actual human discomfort (p < 0.001). In addition, the DI of SDOD was much lower than that of DOD. FIO₂ of SDOD was 2-5% less than that of CFO. In conclusion, SDOD might provide more comfortable oxygen delivery by reducing DI, and conserves oxygen while offering an equivalent FIO₂.
Authors:
Gil Jun Lee; Yeon-Mok Oh; Seung Kwon Oh; Choongsoo S Shin; Tae Soo Lee
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-8-16
Journal Detail:
Title:  Respiratory care     Volume:  -     ISSN:  0020-1324     ISO Abbreviation:  Respir Care     Publication Date:  2012 Aug 
Date Detail:
Created Date:  2012-8-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  7510357     Medline TA:  Respir Care     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
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