Document Detail


Synapsin I-like immunoreactivity in nerve fibers associated with lingual taste buds of the rat.
MedLine Citation:
PMID:  2108194     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Immunoreactivity to synapsin I, a neuronal phosphoprotein, was localized in free-floating tissue sections prepared from lingual tissue of rats. Many nerve fibers within the tissue exhibited clear immunoreactivity including motor endplates on striated muscle, autonomic fibers innervating blood vessels or glands, and sensory fibers innervating muscles or the lingual epithelium including taste buds. Numerous immunoreactive fibers occurred within each taste bud, with fewer, fine fibers being dispersed in the epithelium between taste buds. The majority of the intragemmal immunoreactive fibers extended throughout the taste buds most of the distance outward from the basal lamina toward the surface of the epithelium. Fine, perigemmal fibers reached nearly to the epithelial surface. Ultrastructural analysis of the immunoreactive sensory fibers revealed that synapsin I-immunoreactivity occurred diffusely throughout the cytoplasm, and heavily in association with microvesicles. The synaptic vesicles at the taste receptor cell-to-afferent fiber synapse were, however, not immunoreactive for synapsin I, although these vesicles fall into the size class shown to be immunoreactive in other systems. This absence of synapsin I may be a common property of vesicles in axonless short receptor cells.
Authors:
T E Finger; M Womble; J C Kinnamon; T Ueda
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  The Journal of comparative neurology     Volume:  292     ISSN:  0021-9967     ISO Abbreviation:  J. Comp. Neurol.     Publication Date:  1990 Feb 
Date Detail:
Created Date:  1990-05-02     Completed Date:  1990-05-02     Revised Date:  2007-11-14    
Medline Journal Info:
Nlm Unique ID:  0406041     Medline TA:  J Comp Neurol     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  283-90     Citation Subset:  IM    
Affiliation:
Department of Cellular & Structural Biology, University of Colorado School of Medicine, Denver 80262.
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MeSH Terms
Descriptor/Qualifier:
Animals
Immunohistochemistry
Microscopy, Electron
Nerve Tissue Proteins / metabolism*
Neurons, Afferent / metabolism*,  ultrastructure
Rats
Synapsins
Taste Buds / ultrastructure*
Tongue / innervation*,  ultrastructure
Grant Support
ID/Acronym/Agency:
NS 00772/NS/NINDS NIH HHS; NS 20486/NS/NINDS NIH HHS; NS 23326/NS/NINDS NIH HHS
Chemical
Reg. No./Substance:
0/Nerve Tissue Proteins; 0/Synapsins

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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