Document Detail

Symptoms and signs in culture-proven acute maxillary sinusitis in a general practice population.
MedLine Citation:
PMID:  19775340     Owner:  NLM     Status:  MEDLINE    
The objective of this study was to assess symptoms and signs in patients with maxillary sinusitis and a bacteriological diagnosis obtained by sinus aspiration or lavage. Designed as a prospective cohort study in general practice, the study included 174 patients, aged 18-65 years, suspected of having acute maxillary sinusitis by their general practitioner. The main outcome measures were the independent association of symptoms, signs, erythrocyte sedimentation rate (ESR), and C-reactive protein (CRP) concentration and confirmed infection with the predominant bacterial pathogens Streptococcus pneumoniae and Haemophilus influenzae. The predominant organisms found in patients with acute maxillary sinusitis were S. pneumoniae and H. influenzae. Body temperature >38 degrees C and maxillary toothache were significantly associated with the presence of S. pneumoniae and H. influenzae. Positive bacteriological culture results were significantly associated with increasing ESR and CRP values. None of the symptoms and signs, with the exception of body temperature >38 degrees C and maxillary toothache, were particularly sensitive indicators of the specific aetiology in patients with acute maxillary sinusitis. Elevated ESR and CRP values were significantly associated with positive bacteriological culture results. On the other hand, absence of these symptoms and signs did not exclude the presence of acute maxillary sinusitis.
Jens Georg Hansen; Tove Højbjerg; Jørn Rosborg
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  APMIS : acta pathologica, microbiologica, et immunologica Scandinavica     Volume:  117     ISSN:  1600-0463     ISO Abbreviation:  APMIS     Publication Date:  2009 Oct 
Date Detail:
Created Date:  2009-09-24     Completed Date:  2009-10-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8803400     Medline TA:  APMIS     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  724-9     Citation Subset:  IM    
General Practice Lindenborgvej, Lindenborgvej 93, Aalborg SV, Denmark.
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MeSH Terms
Acute Disease
Blood Sedimentation
C-Reactive Protein / analysis
Cohort Studies
Family Practice
Haemophilus influenzae / isolation & purification
Maxillary Sinusitis / blood,  diagnosis*,  microbiology
Middle Aged
Prospective Studies
Streptococcus pneumoniae / isolation & purification
Reg. No./Substance:
9007-41-4/C-Reactive Protein

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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