| Symptoms and lung function in health care personnel exposed to glutaraldehyde. | |
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MedLine Citation:
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PMID: 12541275 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Glutaraldehyde is widely used as a disinfectant for endoscopic equipment. The aim of this study was to investigate work practices and glutaraldehyde exposure in relation to symptoms and lung function. METHODS: A questionnaire was administered to 76 nurses. Exposed nurses (n = 38) also completed lung function tests and visual analogue scales before and after a work session in which glutaraldehyde exposure occurred. Disinfection activities were timed and counted, personal exposures established, and control measures documented. RESULTS: Exposure values above the exposure limit (0.10 ppm) were found for all exposure control methods except for the enclosed washing machine. Skin symptoms were 3.6 times more likely to be reported by exposed workers. None of the other symptoms were significantly associated with glutaraldehyde exposure. There were significant cross-shift reductions in FVC and FEV(1) in the exposed group. No evidence of a dose-response relationship for symptoms or lung function was found. CONCLUSIONS: Further exposure controls for both glutaraldehyde and gloves are required to improve skin care in glutaraldehyde exposed nurses. Exposure monitoring methods also need review. |
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Authors:
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Andrew Waters; Jeremy Beach; Michael Abramson |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: American journal of industrial medicine Volume: 43 ISSN: 0271-3586 ISO Abbreviation: Am. J. Ind. Med. Publication Date: 2003 Feb |
Date Detail:
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Created Date: 2003-01-23 Completed Date: 2003-05-22 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8101110 Medline TA: Am J Ind Med Country: United States |
Other Details:
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Languages: eng Pagination: 196-203 Citation Subset: IM |
Copyright Information:
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Copyright 2003 Wiley-Liss, Inc. |
Affiliation:
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Department of Epidemiology and Preventive Medicine, Monash University, Melbourne, Australia. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Dermatitis, Occupational / etiology* Disinfectants / adverse effects* Female Forced Expiratory Volume / drug effects Glutaral / adverse effects* Humans Logistic Models Male Nurses* Occupational Exposure / adverse effects*, analysis Odds Ratio Pain Measurement Questionnaires Respiratory Function Tests |
| Chemical | |
Reg. No./Substance:
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0/Disinfectants; 111-30-8/Glutaral |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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