Document Detail

Symptoms and diagnosis of asthma in a general population – longitudinal results from the SHIP database.
MedLine Citation:
PMID:  20846083     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Against the background of an increasing prevalence of allergies, the epidemiology of asthma in relation to age is still a matter of debate. To further clarify the prevalence of asthma, asthmatic symptoms, and their change over time within a population sample, we analyzed longitudinal data from the Study of Health in Pomerania (SHIP).
METHODS: Standardized questionnaires for asthma and asthmatic symptoms were available in 4310 individuals aged 20–79 years [corrected]. The population sample underwent a 5-year follow-up with 3300 subjects reexamined. The questionnaire evaluated estimates to describe the prevalence in wheeze, chest tightness, shortness of breath, coughing, nocturnal symptoms, and asthma attacks in the past 12 months, current medications, current asthma, and nasal allergies at baseline and its longitudinal net change.
RESULTS: The prevalence of current asthma at the baseline study was 1.8% [95% confidence interval (CI 1.4–2.2)], those of nasal allergies 16.7% (95% CI 15.6–17.9). Sixteen percent of asthmatic individuals were not medically treated. The net changes in asthmatic symptoms per 60 months of follow-up ranged between a decrease by 2.0% (chest tightness at night) and an increase by 1.2% (nocturnal attack of coughing). The proportions of subjects with current asthma remained unchanged. The prevalence of current asthma and symptoms was higher in young individuals, whereas the net change over time was slightly increasing at the age of 36 and above.
CONCLUSION: Despite the fact of a high prevalence of subjects complaining of nasal allergies, the overall prevalence of current asthma remained low over time. The prevalence in asthma and asthmatic symptoms as well as its net changes over 5 years were age dependent.
Christoph Schäper; Sven Gläser; Anne Obst; Carsten O Schmidt; Henry Völzke; Stephan B Felix; Ralf Ewert; Beate Koch
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  The Journal of asthma : official journal of the Association for the Care of Asthma     Volume:  47     ISSN:  1532-4303     ISO Abbreviation:  J Asthma     Publication Date:  2010 Oct 
Date Detail:
Created Date:  2010-10-05     Completed Date:  2010-11-04     Revised Date:  2010-11-22    
Medline Journal Info:
Nlm Unique ID:  8106454     Medline TA:  J Asthma     Country:  England    
Other Details:
Languages:  eng     Pagination:  860-4     Citation Subset:  IM    
Department of Internal Medicine B – Cardiology, Intensive Care, Pulmonary Medicine and Infectious Diseases, University of Greifswald, Greifswald, Germany.
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MeSH Terms
Asthma / diagnosis*,  epidemiology,  physiopathology
Cohort Studies
Cough / epidemiology,  physiopathology
Dyspnea / epidemiology,  physiopathology
Follow-Up Studies
Germany / epidemiology
Longitudinal Studies
Middle Aged
Odds Ratio
Respiratory Sounds / physiopathology
Young Adult
Erratum In:
J Asthma. 2010 Nov;47(9):1065

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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