| Symptoms of atrial fibrillation in patients with and without subsequent permanent atrial fibrillation based on a retrospective questionnaire survey. | |
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MedLine Citation:
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PMID: 20716840 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The aim of the present study was to determine whether symptoms of atrial fibrillation (AF) differ between patients with and without subsequent permanent AF. Sixty-four patients (68 +/- 10 years old, 45 males) were recruited. AF follow-up was started at the age of 61 +/- 10 years and accomplished in a median period of 4.9 years (396 person-years). Permanent AF, defined as lasting > 180 days, developed in 17 patients (14 males) (43 per 1000 person-years). The AF follow-up period was longer in the permanent AF group than in the non-permanent AF group (median, 9.8 versus 4.2 years, P < 0.001). For baseline characteristics, hypertension was less frequent in the permanent AF group than in the nonpermanent AF group (18% versus 45%, P < 0.05). A retrospective questionnaire survey regarding initial AF symptoms was conducted. The severity of AF symptoms by a 4-grade scale was significantly milder in the permanent AF group than in the nonpermanent AF group (P < 0.05). Cox proportional hazards model analysis revealed that the severity of initial AF symptoms was related to the subsequent development of permanent AF (hazard ratio 0.46 per grade, 95% confidence interval 0.23 - 0.93, P < 0.05), but age, gender, hypertension, diabetes mellitus, organic heart disease, and left atrial dimension were not. The permanent AF-free rate was significantly lower in 33 patients with mild symptoms than in 31 patients with severe symptoms (log-rank test, P < 0.05). These results point to an inconspicuous feature in the development of permanent AF. |
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Authors:
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Tokuhiro Kawara; Jun Narumi; Kenzo Hirao; Kenji Kasuya; Mihoko Kawabata; Naoko Tojo; Mitsuaki Isobe; Masato Matsuura |
Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: International heart journal Volume: 51 ISSN: 1349-2365 ISO Abbreviation: Int Heart J Publication Date: 2010 Jul |
Date Detail:
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Created Date: 2010-08-18 Completed Date: 2010-12-10 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 101244240 Medline TA: Int Heart J Country: Japan |
Other Details:
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Languages: eng Pagination: 242-6 Citation Subset: IM |
Affiliation:
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Department of Biofunctional Informatics, Graduate School of Health Care Sciences, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Aged Aged, 80 and over Atrial Fibrillation / complications*, diagnosis*, therapy Cohort Studies Female Health Surveys Humans Male Middle Aged Prognosis Proportional Hazards Models Questionnaires Recurrence Retrospective Studies Risk Factors Severity of Illness Index |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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