Document Detail


Symptomatic vertebral hemangioma: treatment with radiotherapy.
MedLine Citation:
PMID:  20622368     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND: Vertebrae are the second commonest site among skeletal locations affected by hemangioma, but only about one per cent becomes symptomatic throughout the life. Though surgery, intra vertebral injection of various sclerosing agents have been tried in treating this benign process, no general consensus regarding management has been reached. Radiotherapy is emerging as a low cost, simple, non-invasive but very effective modality of treatment of symptomatic vertebral hemangioma. AIM: This study aims to find out the role of external beam radiotherapy in alleviating the symptoms of symptomatic vertebral hemangiomas without compromising the quality of life. MATERIALS AND METHODS: Seven consecutive patients with symptomatic vertebral hemangioma were treated with a fixed dose of external beam radiotherapy; and muscle power was assessed before, after treatment and during follow-up. RESULTS: All patients showed improvement of muscle power, which increased with the passage of time. Pain relief with improvement of quality of life was obtained in all the patients. CONCLUSION: Effect of radiotherapy on vertebral hemangioma is dose-dependent and the dose limiting factor is the spinal cord tolerance. In the present era of IMRT, greater dose can be delivered to the parts of vertebra affected by the hemangioma without compromising the spinal cord tolerance and expected to give better results.
Authors:
Ranen K Aich; Asit R Deb; Abhijit Banerjee; Rejaul Karim; Phalguni Gupta
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Journal of cancer research and therapeutics     Volume:  6     ISSN:  1998-4138     ISO Abbreviation:  J Cancer Res Ther     Publication Date:    2010 Apr-Jun
Date Detail:
Created Date:  2010-07-12     Completed Date:  2010-10-28     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101249598     Medline TA:  J Cancer Res Ther     Country:  India    
Other Details:
Languages:  eng     Pagination:  199-203     Citation Subset:  IM    
Affiliation:
Department of Radiotherapy, Nil Ratan Sirkar Medical College, Kolkata, India.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Female
Hemangioma / radiotherapy*
Humans
Lumbar Vertebrae / radiation effects*
Male
Middle Aged
Muscle Weakness / pathology*
Radiotherapy Dosage
Spinal Neoplasms / radiotherapy*
Treatment Outcome

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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