Document Detail

Symptomatic and silent gall stones in the community.
MedLine Citation:
PMID:  2013429     Owner:  NLM     Status:  MEDLINE    
The prevalence of gall stone disease in a stratified random sample of 1896 British adults (72.2% of those approached) was established using real time ultrasound. The prevalence rose with age, except in women of 40-49 years, so that at 60-69 years, 22.4% of women and 11.5% of men had gall stones or had undergone cholecystectomy. The cholecystectomy rate of people with gall stone disease was higher in women than in men (43.5% v 24%, p less than 0.05). Very few subjects with gall stones had convincing biliary symptoms. In women, 10.4% had symptoms according to a questionnaire definition of biliary pain and 6.3% according to conventional history taking, while no men at all admitted to biliary pain. Nevertheless, cholecystectomy in men had nearly always been preceded by convincing biliary symptoms. The age at cholecystectomy was, on average, nine years less than the age at detection of silent gall stones in both sexes. It is concluded that either gall stones are especially prone to cause symptoms in younger people or that there are two kinds of cholelithiasis - symptomatic and silent. The lack of symptomatic gall stones in cross sectional surveys is probably due to their rapid diagnosis and treatment.
K W Heaton; F E Braddon; R A Mountford; A O Hughes; P M Emmett
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Gut     Volume:  32     ISSN:  0017-5749     ISO Abbreviation:  Gut     Publication Date:  1991 Mar 
Date Detail:
Created Date:  1991-05-15     Completed Date:  1991-05-15     Revised Date:  2009-11-18    
Medline Journal Info:
Nlm Unique ID:  2985108R     Medline TA:  Gut     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  316-20     Citation Subset:  AIM; IM    
University Department of Medicine, Bristol Royal Infirmary.
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MeSH Terms
Age Factors
Cholelithiasis / epidemiology*,  surgery,  ultrasonography
Cross-Sectional Studies
Great Britain / epidemiology
Middle Aged
Sex Factors

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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