Document Detail


Symptomatic-enlarging hepatic hemangiomas are effectively treated by percutaneous ultrasonography-guided radiofrequency ablation.
MedLine Citation:
PMID:  21115209     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
BACKGROUND & AIMS: We aimed to evaluate the feasibility, efficacy, and safety of percutaneous ultrasonography-guided radiofrequency ablation for the management of symptomatic-enlarging hepatic hemangiomas.
METHODS: Twenty-four patients (5 male and 19 female, with mean age of 49.5±2.2) with 25 hemangiomas over 4 cm underwent percutaneous RFA due to either the presence of symptoms or the enlargement of hemangioma compared with previous imaging studies.
RESULTS: The mean diameter of hemangioma was 7.2±0.7 cm (4.0-15.0 cm) with 16 hemangiomas in right and 9 hemangiomas in left lobe. Twenty-three hemangiomas (92.0%) were successfully treated by radiofrequency ablation. The mean diameter of hemangiomas was decreased to 4.5±2.4 cm (p<0.001) in serial follow-up CT scans over mean period of 23±3.8 months (23-114 months). Symptoms related to hemangioma disappeared without enlargement of hemangiomas in all successfully treated patients. There were 14 adverse events in 10 patients including abdominal pain, indirect hyperbilirubinemia (>3.0 mg/dl), fever (38.3°C), anemia (<10 g/dl), and ascites, which were successfully managed by conservative treatment.
CONCLUSIONS: Percutaneous ultrasonography-guided radiofrequency ablation is an effective, minimally invasive, and safe procedure for the management of symptomatic-enlarging hepatic hemangioma.
Authors:
Soo Young Park; Won Young Tak; Min Kyu Jung; Seong Woo Jeon; Chang Min Cho; Young Oh Kweon; Kab Chul Kim
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Publication Detail:
Type:  Journal Article     Date:  2010-09-29
Journal Detail:
Title:  Journal of hepatology     Volume:  54     ISSN:  1600-0641     ISO Abbreviation:  J. Hepatol.     Publication Date:  2011 Mar 
Date Detail:
Created Date:  2011-02-18     Completed Date:  2011-06-21     Revised Date:  2012-08-24    
Medline Journal Info:
Nlm Unique ID:  8503886     Medline TA:  J Hepatol     Country:  England    
Other Details:
Languages:  eng     Pagination:  559-65     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 European Association for the Study of the Liver. Published by Elsevier B.V. All rights reserved.
Affiliation:
Department of Gastroenterology and Hepatology, Liver Research Institute, Kyungpook National University, Daegu, Republic of Korea.
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Catheter Ablation / methods*
Female
Hemangioma / pathology,  radiography,  surgery*,  ultrasonography
Humans
Liver Neoplasms / pathology,  radiography,  surgery*,  ultrasonography
Male
Middle Aged
Radio Waves / therapeutic use*
Tomography, X-Ray Computed
Treatment Outcome
Ultrasonography, Interventional / methods

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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