| Symptomatic atlantoaxial subluxation in persons with Down syndrome. | |
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MedLine Citation:
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PMID: 6239875 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a prospective study 40 of 236 individuals with Down syndrome were found to have atlantoaxial instability. Whereas most of the 40 affected children were asymptomatic, seven patients exhibited various neuropathology. Historical data, neurologic findings, radiologic interpretations, and surgical management of these seven patients are described in detail. In addition, case reports of other individuals with Down syndrome and symptomatic atlantoaxial subluxation from the literature were analyzed. We conclude that early identification of these patients and appropriate surgical management, including reduction of the subluxation and posterior cervical spine fusion, will in most instances result in a favorable outcome; however, patients with long-standing symptoms and marked neuronal damage show no or only little improvement postoperatively. |
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Authors:
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S M Pueschel; J H Herndon; M M Gelch; K E Senft; F H Scola; M J Goldberg |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Journal of pediatric orthopedics Volume: 4 ISSN: 0271-6798 ISO Abbreviation: J Pediatr Orthop Publication Date: 1984 Nov |
Date Detail:
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Created Date: 1985-02-05 Completed Date: 1985-02-05 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 8109053 Medline TA: J Pediatr Orthop Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 682-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Atlanto-Axial Joint / injuries* Child Dislocations / diagnosis, etiology*, surgery Down Syndrome / complications* Female Humans Joint Instability / diagnosis, etiology*, surgery Male Middle Aged Prospective Studies Spinal Fusion |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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