Document Detail


Symptomatic adrenal insufficiency during inhaled corticosteroid treatment.
MedLine Citation:
PMID:  11567945     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Symptomatic adrenal insufficiency, presenting as hypoglycaemia or poor weight gain, may occur on withdrawal of corticosteroid treatment but has not previously been reported during inhaled corticosteroid treatment. This case series illustrates the occurrence of clinically significant adrenal insufficiency in asthmatic children while patients were on inhaled corticosteroid treatment and the unexpected modes of presentation. General practitioners and paediatricians need to be aware that this unusual but acute serious complication may occur in patients treated with inhaled corticosteroids.
Authors:
L Patel; J K Wales; M S Kibirige; A A Massarano; J M Couriel; P E Clayton
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Archives of disease in childhood     Volume:  85     ISSN:  1468-2044     ISO Abbreviation:  Arch. Dis. Child.     Publication Date:  2001 Oct 
Date Detail:
Created Date:  2001-09-24     Completed Date:  2001-10-04     Revised Date:  2008-11-20    
Medline Journal Info:
Nlm Unique ID:  0372434     Medline TA:  Arch Dis Child     Country:  England    
Other Details:
Languages:  eng     Pagination:  330-4     Citation Subset:  AIM; IM    
Affiliation:
Department of Child Health, University of Manchester, Booth Hall Childrens Hospital, Manchester M9 7AA, UK. lp@man.ac.uk
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MeSH Terms
Descriptor/Qualifier:
Administration, Inhalation
Administration, Topical
Adrenal Insufficiency / chemically induced*,  diagnosis
Adrenocorticotropic Hormone / diagnostic use
Androstadienes / adverse effects
Anti-Inflammatory Agents / adverse effects*
Asthma / complications,  drug therapy*
Beclomethasone / adverse effects
Budesonide / adverse effects
Child
Child, Preschool
Female
Humans
Hydrocortisone / blood,  urine
Male
Chemical
Reg. No./Substance:
0/Androstadienes; 0/Anti-Inflammatory Agents; 4419-39-0/Beclomethasone; 50-23-7/Hydrocortisone; 51333-22-3/Budesonide; 9002-60-2/Adrenocorticotropic Hormone; 90566-53-3/fluticasone

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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