Document Detail

Symptom distress in older adults following cancer surgery.
MedLine Citation:
PMID:  23047803     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Symptom distress remains a significant health problem among older adults with cancer following surgery. Understanding factors influencing older adults' symptom distress may lead to early identification and interventions, decreasing morbidity and improving outcomes.
OBJECTIVE: We conducted this study to identify factors associated with symptom distress following surgery among 326 community-residing patients 65 years or older with a diagnosis of thoracic, digestive, gynecologic, and genitourinary cancers.
METHODS: This secondary analysis used combined subsets of data from 5 nurse-directed intervention clinical trials targeting patients after surgery at academic cancer centers in northwest and northeastern United States. Symptom distress was assessed by the Symptom Distress Scale at baseline and at 3 and 6 months.
RESULTS: A multivariable analysis, using generalized estimating equations, showed that symptom distress was significantly less at 3 and 6 months (3 months: P < .001, 6 months: P = .002) than at baseline while controlling for demographic, biologic, psychological, treatment, and function covariates. Thoracic cancer, comorbidities, worse mental health, and decreased function were, on average, associated with increased symptom distress (all P < .05). Participants 75 years or older reported increased symptom distress over time compared with those aged 65 to 69 years (P < .05).
CONCLUSIONS: Age, type of cancer, comorbidities, mental health, and function may influence older adults' symptom distress following cancer surgery.
IMPLICATIONS FOR PRACTICE: Older adults generally experience decreasing symptom distress after thoracic, abdominal, or pelvic cancer surgery. Symptom management over time for those with thoracic cancer, comorbidities, those with worse mental health, those with decreased function, and those 75 years or older may prevent morbidity and improve outcomes of older adults following surgery.
Janet H Van Cleave; Brian L Egleston; Elizabeth Ercolano; Ruth McCorkle
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Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Cancer nursing     Volume:  36     ISSN:  1538-9804     ISO Abbreviation:  Cancer Nurs     Publication Date:    2013 Jul-Aug
Date Detail:
Created Date:  2013-06-18     Completed Date:  2014-05-06     Revised Date:  2014-07-02    
Medline Journal Info:
Nlm Unique ID:  7805358     Medline TA:  Cancer Nurs     Country:  United States    
Other Details:
Languages:  eng     Pagination:  292-300     Citation Subset:  IM; N    
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MeSH Terms
Aged, 80 and over
Behavioral Symptoms / diagnosis*,  epidemiology
Cohort Studies
Databases, Factual
Depression / diagnosis,  epidemiology*,  psychology
Digestive System Neoplasms / pathology,  psychology,  surgery
Disease Progression
Fatigue / diagnosis,  epidemiology,  physiopathology,  psychology
Genital Neoplasms, Female / pathology,  psychology,  surgery
Geriatric Assessment*
Neoplasms / pathology,  psychology,  surgery*
Pain / diagnosis,  epidemiology,  physiopathology,  psychology
Postoperative Complications / physiopathology,  psychology*
Retrospective Studies
Risk Assessment
Sickness Impact Profile
Stress, Psychological / diagnosis*,  epidemiology
Thoracic Neoplasms / pathology,  psychology,  surgery
Time Factors
Grant Support
P30 CA006927/CA/NCI NIH HHS; P30 CA006927/CA/NCI NIH HHS; T32 NR008346/NR/NINR NIH HHS; T32 NR008346/NR/NINR NIH HHS; T32 NR009356/NR/NINR NIH HHS

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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