Document Detail

Sympathetic skin response in amyotrophic lateral sclerosis.
MedLine Citation:
PMID:  9808278     Owner:  NLM     Status:  MEDLINE    
OBJECTIVES: The aim of our study was to verify the usefulness of the sympathetic skin response (SSR) as an instrument for assessing autonomic involvement in amyotrophic lateral sclerosis (ALS). MATERIAL AND METHODS: - We studied palmar and plantar SSR in 31 patients with ALS (mean age: 58.4+/-9.3 years); 48 age-matched healthy subjects constituted the control group. RESULTS: Palmar SSR was elicitable in all patients, and its latency and amplitude did not significantly differ from that of the controls. Plantar response was evoked in all but 7 patients. The lack of response was significantly related to the functional disability and duration of the disease. CONCLUSIONS: We conclude that SSR, even the plantar response, cannot be considered a useful tool for detecting early autonomic involvement in ALS.
G Miscio; F Pisano
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article    
Journal Detail:
Title:  Acta neurologica Scandinavica     Volume:  98     ISSN:  0001-6314     ISO Abbreviation:  Acta Neurol. Scand.     Publication Date:  1998 Oct 
Date Detail:
Created Date:  1999-01-07     Completed Date:  1999-01-07     Revised Date:  2006-08-16    
Medline Journal Info:
Nlm Unique ID:  0370336     Medline TA:  Acta Neurol Scand     Country:  DENMARK    
Other Details:
Languages:  eng     Pagination:  276-9     Citation Subset:  IM    
Department of Neurology, Salvatore Maugeri Foundation, IRCCS, Rehabilitation Institute, Veruno (NO), Italy.
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MeSH Terms
Amyotrophic Lateral Sclerosis / diagnosis,  physiopathology*
Disease Progression
Galvanic Skin Response / physiology*
Middle Aged
Neural Conduction / physiology
Reaction Time
Reproducibility of Results
Severity of Illness Index
Sympathetic Nervous System / physiopathology*

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