| Sympathetic cutaneous vasomotor alerting responses (SCVARs) are associated with hippocampal theta rhythm in non-moving conscious rats. | |
| | |
MedLine Citation:
|
PMID: 19699727 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Alerting stimuli that cause sympathetic cutaneous vasomotor alerting responses ("SCVARs") in the thermoregulatory vascular bed of the rabbit ear pinna also induce theta (5-8 Hz) rhythm in the hippocampal EEG, a marker that the animal is engaged with the environment. The present study determines the relation between SCVARs in the thermoregulatory tail artery vascular bed and hippocampal EEG theta rhythm in Sprague-Dawley rats. A Doppler ultrasonic flow probe chronically implanted around the base of the tail artery was used to measure SCVARs. Unipolar electrodes were implanted in the hippocampus (CA1 region) to measure EEG. Six standard non-noxious brief alerting stimuli were administered during continuous recording of tail blood flow and EEG. The SCVAR index was calculated as the percentage fall from pre-alerting blood flow values. After stimuli the SCVAR index for the tail artery blood flow was 84+/-2% of the pre-alerting control. In contrast, the same stimuli caused little fall in blood flow within the superior mesenteric bed (SCVAR index=18+/-2%). The proportion of theta power in the total frequency range (0-20 Hz) increased significantly after alerting stimuli (46+/-2% vs. 29+/-1% before stimuli, p<0.05). Theta proportion began to increase approximately 0.5 s after the stimuli and preceded SCVARs by approximately 1 s. The SCVAR index was correlated with the magnitude of the increment in theta power. Our study demonstrates that alerting responses resulting in selective vasoconstriction of the tail vascular bed are associated with hippocampal theta rhythm in conscious rats. |
| | |
Authors:
|
Rodrigo Cunha Alvim de Menezes; Youichirou Ootsuka; William W Blessing |
Related Documents
:
|
7745417 - Dementia associated with bilateral carotid occlusions: neuropsychological and haemodyna... 7863027 - Spect measurements of cerebral blood volume before and after acetazolamide in occlusive... 1993017 - Frontal impairment and hypoperfusion in neuroacanthocytosis. 10779017 - Temporal changes of the apparent diffusion coefficients of water and metabolites in rat... 6775647 - Blood-gas tension measurement in anaesthesia by bubble equilibration and mass spectrome... 12582147 - Acutely altered hemodynamics following venous obstruction in the early chick embryo. |
Publication Detail:
|
Type: Journal Article Date: 2009-08-21 |
Journal Detail:
|
Title: Brain research Volume: 1298 ISSN: 1872-6240 ISO Abbreviation: Brain Res. Publication Date: 2009 Nov |
Date Detail:
|
Created Date: 2009-10-12 Completed Date: 2009-12-16 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 0045503 Medline TA: Brain Res Country: Netherlands |
Other Details:
|
Languages: eng Pagination: 123-30 Citation Subset: IM |
Affiliation:
|
Centre for Neuroscience, Departments of Physiology and Medicine, Flinders University, Adelaide, SA, Australia. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Analysis of Variance Animals Blood Flow Velocity Electrodes, Implanted Electroencephalography Hippocampus / physiology* Laser-Doppler Flowmetry Male Rats Rats, Sprague-Dawley Regional Blood Flow / physiology* Signal Processing, Computer-Assisted Skin / blood supply* Staining and Labeling Tail / blood supply Theta Rhythm* Vasoconstriction / physiology* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Nitric oxide alters GABAergic synaptic transmission in cultured hippocampal neurons.
Next Document: Modulatory role of lipoic acid on lipopolysaccharide-induced oxidative stress in adult rat Sertoli c...