Document Detail

Sweet's syndrome with neurologic manifestation: case report and literature review.
MedLine Citation:
PMID:  12786869     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Sweet's syndrome with involvement of the central nervous system (CNS) is rarely reported. METHODS: We describe a Japanese woman with Sweet's syndrome associated with acute-onset encephalitis and review literatures. RESULTS: Examination of the cerebrospinal fluid (CSF) revealed pleocytosis with lymphocytes predominant. Magnetic resonance imaging (MRI) revealed increased signal intensity on T2-weighted scans in the left temporal lobe. To our knowledge, 22 cases of Sweet's syndrome associated with CNS involvement have been reported. The mean age is 47.6 years (n = 22). Sex distribution (male : female) is 12 : 10 (n = 22). The most common neurologic symptoms are convulsions, headaches, and disturbance of consciousness. CSF cell count is increased with lymphocytes predominant in 8 cases (n = 12). Certain (HLA) types (B54 and Cw1) may be characteristic findings in Sweet's syndrome accompanied with the CNS involvement in Japanese patients, as these were found in four previous cases similar to the present case. CONCLUSIONS: Although Sweet's syndrome with neurologic manifestations is rarely reported, it may be needed to investigate neurologic manifestations.
Yoshimasa Nobeyama; Ryoichi Kamide
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Publication Detail:
Type:  Case Reports; Journal Article; Review    
Journal Detail:
Title:  International journal of dermatology     Volume:  42     ISSN:  0011-9059     ISO Abbreviation:  Int. J. Dermatol.     Publication Date:  2003 Jun 
Date Detail:
Created Date:  2003-06-05     Completed Date:  2003-11-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  0243704     Medline TA:  Int J Dermatol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  438-43     Citation Subset:  IM    
Department of Dermatology, Jikei University School of Medicine, Tokyo, Japan.
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MeSH Terms
Acute Disease
Cerebrospinal Fluid / chemistry
Encephalitis / complications,  diagnosis,  immunology*
Magnetic Resonance Imaging
Middle Aged
Sweet Syndrome / complications*,  diagnosis,  immunology*

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