Document Detail


Sweet syndrome associated with hydralazine-induced lupus erythematosus.
MedLine Citation:
PMID:  22530328     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Sweet syndrome (SS) is a distinctive but poorly understood clinical syndrome, which likely represents an immunologic reaction pattern to a wide range of underlying or preceding conditions, including viral illnesses, inflammatory bowel disease, and malignancies. We report the case of a patient who presented with an acute eruption that was clinically and histologically consistent with SS. The patient also met diagnostic criteria for systemic lupus erythematosus with serositis, stomatitis, positive antinuclear antibody (ANA), and positive anti-double-stranded DNA antibodies. Additionally, positive antihistone antibodies and exposure to hydralazine supported the specific diagnosis of drug-induced lupus erythematosus, and we concluded that his SS was a manifestation of hydralazine-induced lupus. We also briefly review the precedence for this unusual dual diagnosis in the literature.
Authors:
Todd V Cartee; Suephy C Chen
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Publication Detail:
Type:  Case Reports; Journal Article    
Journal Detail:
Title:  Cutis     Volume:  89     ISSN:  0011-4162     ISO Abbreviation:  Cutis     Publication Date:  2012 Mar 
Date Detail:
Created Date:  2012-04-25     Completed Date:  2012-05-10     Revised Date:  2013-09-12    
Medline Journal Info:
Nlm Unique ID:  0006440     Medline TA:  Cutis     Country:  United States    
Other Details:
Languages:  eng     Pagination:  121-4     Citation Subset:  IM    
Affiliation:
Department of Dermatology, Emery University, Atlanta, Georgia 30322, USA. tcartee@emory.edu
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MeSH Terms
Descriptor/Qualifier:
Antibodies, Antinuclear / blood
Antihypertensive Agents / adverse effects*
Diagnosis, Differential
Humans
Hydralazine / adverse effects*
Hypertension, Portal / drug therapy
Lupus Erythematosus, Systemic / chemically induced*,  complications,  diagnosis*
Male
Middle Aged
Sweet Syndrome / complications,  diagnosis*
Chemical
Reg. No./Substance:
0/Antibodies, Antinuclear; 0/Antihypertensive Agents; 86-54-4/Hydralazine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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