Document Detail

Swapping genes to survive - a new role for archaeal type IV pili.
MedLine Citation:
PMID:  21992544     Owner:  NLM     Status:  Publisher    
Type IV pili are filamentous structures that are found on the surface of many bacterial and archaeal cells, they are involved in cell motility and surface adhesion. In the crenarchaeon Sulfolobus solfataricus, type IV pili formation is strongly induced by UV irradiation and leads to cellular aggregation. The study by Ajon et al. published in this issue of Molecular Microbiology shows that UV-induced cellular aggregation greatly stimulates the exchange of chromosomal markers among irradiated cells, and that this strategy helps with cell survival. Sulfolobus knockout strains that are incapable of forming pili proved to be deficient in aggregation, and also showed decreased cellular survival after UV irradiation. The UV-induced pili of three different Sulfolobus species had distinct morphologies, and correspondingly these three species were able to aggregate only with their own kind. This work has defined a new role for type IV pili in both the transfer of genes within species and the recovery from UV-induced DNA damage.
Thorsten Allers
Related Documents :
2050274 - Expression of protein kinase c isoforms in various steroidogenic cell types.
8845594 - Catecholamines modulate growth and differentiation of human preosteoclastic cells.
2536794 - Stimulation of granulocytic cell iodination by pine cone antitumor substances.
3479244 - Effects of phorbol ester on translocation and down-regulation of protein kinase c and p...
6594414 - Identification and characterization of mononuclear phagocytes isolated from rat testicu...
22652164 - Listeriolysin o: the swiss army knife of listeria.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-10-12
Journal Detail:
Title:  Molecular microbiology     Volume:  -     ISSN:  1365-2958     ISO Abbreviation:  -     Publication Date:  2011 Oct 
Date Detail:
Created Date:  2011-10-13     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8712028     Medline TA:  Mol Microbiol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2011 Blackwell Publishing Ltd.
School of Biology, University of Nottingham, Queen's Medical Centre, Nottingham NG7 2UH, UK.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Changes in Back Pain After Percutaneous Endoscopic Lumbar Discectomy and Annuloplasty for Lumbar Dis...
Next Document:  Louhi 2010: Special issue on Text and Data Mining of Health Documents.